Description

2-Chloro-5-(Pyrrolidin-2-Yl)Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic scaffold. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within the fields of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Ligand Synthesis: Serves as a building block for creating specialized ligands used in catalysis and biochemical assays.
• Agrochemical Research: Potential application in the development of new crop protection agents and pesticides.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for exploratory synthetic chemistry.

Basic Information

Product Name	2-Chloro-5-(Pyrrolidin-2-Yl)Pyridine
CAS No.	1260664-51-4
Molecular Formula	C9H11ClN2
Molecular Weight	182.65 g/mol
Synonyms	2-Chloro-5-(2-pyrrolidinyl)pyridine; 5-(Pyrrolidin-2-yl)-2-chloropyridine; 2-Chloro-5-(pyrrolidin-2-yl)pyridine; 2-Chloro-5-(2-pyrrolidinyl)pyridine; 2-Chloro-5-(1-pyrrolidinyl)pyridine (isomeric check); Pyridine, 2-chloro-5-(2-pyrrolidinyl)-; (2-Pyridinyl)-2-pyrrolidine, 5-chloro derivative
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(Pyrrolidin-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.