Description

1H-Pyrrolo[3,2-B]Pyridine, 2,3-Dihydro-6-(Trifluoromethyl)- is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique chemical properties imparted by the fused pyrrolopyridine scaffold and the strategically positioned trifluoromethyl group, which is crucial for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets, kinase inhibitors, and anti-infective agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Acts as a building block for creating advanced organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1H-Pyrrolo[3,2-B]Pyridine, 2,3-Dihydro-6-(Trifluoromethyl)-
CAS No.	1260664-09-2
Molecular Formula	C8H7F3N2
Molecular Weight	188.15 g/mol
Synonyms	2,3-Dihydro-6-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine; 6-(Trifluoromethyl)-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridine, 2,3-dihydro-6-(trifluoromethyl)-; Dihydro-6-(trifluoromethyl)pyrrolopyridine; Fluorinated Pyrrolopyridine Derivative
EINECS	Contact for details

Quality Control

Every batch of 1H-Pyrrolo[3,2-B]Pyridine, 2,3-Dihydro-6-(Trifluoromethyl)- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.