Description

5H-Pyrano[4,3-B]Pyridine, 2-Chloro-7,8-Dihydro- is a high-purity, advanced pharmaceutical intermediate with the CAS number 1260663-71-5. This heterocyclic compound is a critical building block in modern medicinal chemistry, valued for its unique fused-ring scaffold that enables the synthesis of novel bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in early-stage drug discovery.
• Organic Synthesis Building Block: Employed in the construction of complex nitrogen- and oxygen-containing heterocycles for agrochemical and material science applications.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for methodological development and the exploration of new chemical reactions.

Basic Information

Product Name	5H-Pyrano[4,3-B]Pyridine, 2-Chloro-7,8-Dihydro-
CAS No.	1260663-71-5
Molecular Formula	C8H8ClNO
Molecular Weight	169.61 g/mol
Synonyms	2-Chloro-7,8-dihydro-5H-pyrano[4,3-b]pyridine; 2-Chloro-5H,7H,8H-pyrano[4,3-b]pyridine; 2-Chloro-7,8-dihydro-5H-pyrano[4,3-b]pyridine; 1260663-71-5; AKOS026710693; 2-chloro-7,8-dihydro-5H-pyrano[4,3-b]pyridine; 2-Chloro-5H-pyrano[4,3-b]pyridine, 7,8-dihydro-
EINECS	Contact for details

Quality Control

Our 5H-Pyrano[4,3-B]Pyridine, 2-Chloro-7,8-Dihydro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere for long-term storage to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.