Description

6-Bromo-2-(trifluoromethyl)oxazolo[4,5-b]pyridine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where the oxazolopyridine scaffold offers unique bioactivity and physicochemical properties. It is primarily targeted at the pharmaceutical, agrochemical, and advanced materials industries for applications in medicinal chemistry, crop protection, and organic electronics.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and fungicides, leveraging its halogenated and fluorinated structure.
• Material Science Research: Serves as a precursor for organic semiconductors and light-emitting materials due to its fused heterocyclic core.
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological processes.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Library Synthesis for HTS: A valuable building block for creating diverse compound libraries used in high-throughput screening (HTS) campaigns.

Basic Information

Product Name	6-Bromo-2-(trifluoromethyl)oxazolo[4,5-b]pyridine
CAS No.	1260656-87-8
Molecular Formula	C7H2BrF3N2O
Molecular Weight	266.99 g/mol
Synonyms	6-Bromo-2-(trifluoromethyl)-[1,3]oxazolo[4,5-b]pyridine; 2-(Trifluoromethyl)-6-bromooxazolo[4,5-b]pyridine; Oxazolo[4,5-b]pyridine, 6-bromo-2-(trifluoromethyl)-; 6-Bromo-2-trifluoromethyloxazolo[4,5-b]pyridine
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-(trifluoromethyl)oxazolo[4,5-b]pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.