Description

1,2-Piperidinedicarboxylic Acid, 5-Oxo-, 1-(1,1-Dimethylethyl) Ester is a high-purity, protected amino acid derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetic Chemistry: Used in the design and synthesis of peptide analogs and constrained peptides to improve metabolic stability and bioavailability.
• Protease Inhibitor Synthesis: Serves as a core scaffold or precursor in the development of protease inhibitors for therapeutic applications.
• Agrochemical Research: Employed as a building block for creating novel active ingredients with specific biological activity.
• Ligand and Catalyst Development: Utilized in the synthesis of chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Acts as a precursor for labeled compounds or activity-based probes used in mechanistic studies.

Basic Information

Product Name	1,2-Piperidinedicarboxylic Acid, 5-Oxo-, 1-(1,1-Dimethylethyl) Ester
CAS No.	1260641-46-0
Molecular Formula	C12H19NO5
Molecular Weight	257.28 g/mol
Synonyms	tert-Butyl 5-oxopiperidine-1,2-dicarboxylate; 1-(tert-Butoxycarbonyl)-5-oxopiperidine-2-carboxylic Acid; 5-Oxo-1,2-piperidinedicarboxylic Acid 1-(1,1-Dimethylethyl) Ester; 1-Boc-5-oxopipecolic Acid; Boc-5-oxo-DL-pipecolic Acid; 5-Oxo-1-Boc-pipecolic Acid; 1-N-Boc-5-oxopipecolic Acid
EINECS	Contact for details

Quality Control

Our 1,2-Piperidinedicarboxylic Acid, 5-Oxo-, 1-(1,1-Dimethylethyl) Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.