Description

Azetidine-2-Carboxylic Acid Methyl Ester Oxalate is a high-purity, protected amino acid derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in providing a versatile, stereochemically defined scaffold for constructing complex molecules, enabling precise control over final product structure and activity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals where structural integrity is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, including protease inhibitors and other bioactive molecules.
• Peptidomimetics Research: Used to incorporate constrained azetidine rings into peptide backbones to enhance metabolic stability and biological activity.
• Agrochemical Development: Serves as a building block for creating new generation herbicides and plant growth regulators with specific modes of action.
• Ligand and Catalyst Synthesis: Employed in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to create labeled or modified amino acid analogs for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring high-fidelity, small-ring heterocyclic chemistry.

Basic Information

Product Name	Azetidine-2-Carboxylic Acid Methyl Ester Oxalate
CAS No.	1260641-42-6
Molecular Formula	C7H11NO6
Molecular Weight	205.17 g/mol
Synonyms	Methyl Azetidine-2-carboxylate Oxalate; Methyl 2-Azetidinecarboxylate Oxalate; L-Azetidine-2-carboxylic Acid Methyl Ester Oxalate; (S)-Azetidine-2-carboxylic Acid Methyl Ester Oxalate; Azetidine-2-Carboxylic Acid Methyl Ester, Oxalic Acid Salt; 1-Azetidinecarboxylic Acid, 2-, Methyl Ester, (2S)-, Oxalate (1:1); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our Azetidine-2-Carboxylic Acid Methyl Ester Oxalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency required for research and commercial synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.