Description

1H-Pyrrolo[2,3-C]Pyridine-5-Carboxylic Acid, 4-Fluoro-, Methyl Ester is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it serves as a critical intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). Pharmaceutical R&D teams and fine chemical manufacturers need this precise chemical scaffold to explore new therapeutic agents, leveraging its unique fused pyrrolopyridine core and fluorine substituent for targeted drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent for creating specialized polymers and organic electronic materials.
• Chemical Biology Probe Development: Employed in the design and synthesis of fluorescent tags or molecular probes for studying biological systems.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies in heterocyclic and fluoroorganic chemistry.

Basic Information

Product Name	1H-Pyrrolo[2,3-C]Pyridine-5-Carboxylic Acid, 4-Fluoro-, Methyl Ester
CAS No.	1260386-86-4
Molecular Formula	C10H7FN2O2
Molecular Weight	206.18 g/mol
Synonyms	4-Fluoro-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid methyl ester; Methyl 4-fluoro-1H-pyrrolo[2,3-c]pyridine-5-carboxylate; 4-Fluoro-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid methyl ester; 1H-Pyrrolo[2,3-c]pyridine-5-carboxylic acid, 4-fluoro-, methyl ester; 1260386-86-4; 4-Fluoro-1H-pyrrolo[2,3-c]pyridine-5-methyl carboxylate
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-C]Pyridine-5-Carboxylic Acid, 4-Fluoro-, Methyl Ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and our quality control protocols are designed to meet the stringent requirements of pharmaceutical and advanced chemical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.