Description

5H-Pyrrolo[2,3-C]Pyridin-5-One, 4-Fluoro-1,6-Dihydro- is a high-value fluorinated heterocyclic building block, specifically a pyrrolopyridinone derivative, with the CAS registry number 1260385-25-8. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical R&D teams and fine chemical manufacturers focused on creating new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.

Application

• Pharmaceutical Intermediate: A key scaffold in the synthesis of targeted small-molecule drugs, especially kinase inhibitors.
• Medicinal Chemistry Research: Used extensively in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• API Development: Serves as a core structural element in the development of Active Pharmaceutical Ingredients (APIs).
• Biochemical Tool Compound: Utilized in biochemical assays to study enzyme function and cellular pathways.
• Library Synthesis: Employed for generating diverse compound libraries for high-throughput screening (HTS).
• Agrochemical Research: Potential intermediate in the development of new agrochemicals with enhanced properties.

Basic Information

Product Name	5H-Pyrrolo[2,3-C]Pyridin-5-One, 4-Fluoro-1,6-Dihydro-
CAS No.	1260385-25-8
Molecular Formula	C7H5FN2O
Molecular Weight	152.13 g/mol
Synonyms	4-Fluoro-1,6-dihydro-5H-pyrrolo[2,3-c]pyridin-5-one; 4-Fluoro-5H-pyrrolo[2,3-c]pyridin-5-one; 4-Fluoro-1,6-dihydropyrrolo[2,3-c]pyridin-5-one; 1260385-25-8; 4-Fluoro-5-oxo-1,5-dihydro-6H-pyrrolo[2,3-c]pyridine; 4-Fluoro-6H-pyrrolo[2,3-c]pyridin-5-one
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency for research and development. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.