Description

4-Fluoro-5-Methoxy-7-Azaindole is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique fused ring structure, featuring both nitrogen and fluorine substituents, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents, leveraging the 7-azaindole scaffold's bioisosteric properties.
• Agrochemical Research: Used in developing new generations of herbicides and fungicides, where the fluorine and methoxy groups can modulate bioavailability and activity.
• Material Science: Serves as a building block for organic electronic materials, such as OLED emitters or charge-transport molecules, due to its rigid, conjugated structure.
• Chemical Biology Probe Development: Employed in creating fluorescent tags or molecular probes to study biological pathways and protein interactions.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, particularly in cross-coupling and heterocyclic functionalization reactions.

Basic Information

Product Name	4-Fluoro-5-Methoxy-7-Azaindole
CAS No.	1260385-22-5
Molecular Formula	C8H7FN2O
Molecular Weight	166.15 g/mol
Synonyms	5-Methoxy-4-fluoro-1H-pyrrolo[2,3-b]pyridine; 4-Fluoro-5-methoxy-1H-pyrrolo[2,3-b]pyridine; 7-Azaindole, 4-fluoro-5-methoxy-; 1H-Pyrrolo[2,3-b]pyridine, 4-fluoro-5-methoxy-; 4-Fluoro-5-methoxy-7-azaindole
EINECS	Contact for details

Quality Control

Our 4-Fluoro-5-Methoxy-7-Azaindole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and KF for moisture content, to ensure it meets the exacting standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.