Description

1H-Pyrrolo[2,3-C]Pyridin-5-Amine, 4-Fluoro- is a high-value fluorinated heterocyclic building block, specifically a 4-fluoro derivative of a pyrrolopyridine core. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel bioactive molecules with enhanced properties. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on creating new drug candidates, particularly in oncology and CNS therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors and other targeted small-molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore the impact of fluorine substitution on potency, metabolic stability, and bioavailability.
• Chemical Biology Probes: Serves as a core scaffold for designing fluorescent or affinity probes to study biological pathways and protein function.
• Agrochemical Research: Potential intermediate in the synthesis of advanced, fluorinated active ingredients for crop protection.
• Material Science Precursor: Can be utilized in the synthesis of complex organic molecules for advanced materials, such as organic semiconductors or ligands for catalysis.

Basic Information

Product Name	1H-Pyrrolo[2,3-C]Pyridin-5-Amine, 4-Fluoro-
CAS No.	1260382-22-6
Molecular Formula	C7H6FN3
Molecular Weight	151.14 g/mol
Synonyms	4-Fluoro-1H-pyrrolo[2,3-c]pyridin-5-amine; 4-Fluoro-5-amino-1H-pyrrolo[2,3-c]pyridine; 4-Fluoro-1H-pyrrolo[2,3-c]pyridin-5-ylamine; 5-Amino-4-fluoro-1H-pyrrolo[2,3-c]pyridine; 4-Fluoro-5-aminopyrrolo[2,3-c]pyridine; 1260382-22-6; 4-Fluoro-1H-pyrrolo[2,3-c]pyridin-5-amine (CAS 1260382-22-6)
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-C]Pyridin-5-Amine, 4-Fluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.