Description

6-Bromo-1H-Pyrrolo[3,2-B]Pyridin-3-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with significant value in modern drug discovery. This compound is essential for medicinal chemists developing targeted small-molecule therapies, particularly in oncology and kinase inhibition research. It is primarily utilized by R&D laboratories and large-scale manufacturers in the pharmaceutical and biotechnology sectors for synthesizing novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel kinase inhibitors and other targeted cancer therapeutics.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for drug discovery programs.
• Bioconjugation & Probe Development: Serves as a precursor for creating fluorescent probes or affinity labels for biochemical assays.
• Chemical Biology: Employed in the development of chemical tools to study biological pathways and protein function.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.
• Academic Research: Used in university and institutional labs for fundamental research in heterocyclic chemistry and pharmacology.

Basic Information

Product Name	6-Bromo-1H-Pyrrolo[3,2-B]Pyridin-3-Amine Hydrochloride
CAS No.	1260381-81-4
Molecular Formula	C7H7BrClN3
Molecular Weight	248.51 g/mol
Synonyms	6-Bromo-1H-pyrrolo[3,2-b]pyridin-3-amine hydrochloride; 3-Amino-6-bromo-1H-pyrrolo[3,2-b]pyridine hydrochloride; 6-Bromo-3-amino-1H-pyrrolo[3,2-b]pyridine HCl; 1260381-81-4; 6-Bromo-1H-pyrrolo[3,2-b]pyridin-3-amine HCl salt; 6-Bromo-3-aminopyrrolo[3,2-b]pyridine hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Bromo-1H-Pyrrolo[3,2-B]Pyridin-3-Amine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light brown powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.