Description

7-Bromo-6-Methoxy-5-Azaindole-2-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel, targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis: Used in the preparation of more complex azaindole derivatives and fused heterocyclic systems.
• Biochemical Research: Employed as a tool compound for studying enzyme inhibition and biological pathways.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP-scale production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	7-Bromo-6-Methoxy-5-Azaindole-2-Carboxylic Acid Ethyl Ester
CAS No.	1260381-26-7
Molecular Formula	C11H11BrN2O3
Molecular Weight	299.12 g/mol
Synonyms	Ethyl 7-bromo-6-methoxy-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 7-bromo-6-methoxy-, ethyl ester; 7-Bromo-6-methoxy-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid ethyl ester; 5-Azaindole-2-carboxylic acid, 7-bromo-6-methoxy-, ethyl ester; Ethyl 7-bromo-6-methoxy-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 7-Bromo-6-methoxy-5-aza-indole-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 7-Bromo-6-Methoxy-5-Azaindole-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.