Description

Ethyl 3-(5-Chloro-2-Cyclopropoxyphenyl)-3-Oxopropanoate is a high-value, advanced pharmaceutical intermediate characterized by its specific cyclopropoxy and β-keto ester functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular architectures. It is primarily sought by research institutions and manufacturers in the global pharmaceutical and agrochemical sectors for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug molecules, especially those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its halogenated aromatic structure.
• Chemical Research: Serves as a versatile precursor in organic synthesis for constructing complex heterocycles and fused ring systems in academic and industrial R&D labs.
• API Development: Integral to the process chemistry and scale-up phases for producing target Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) guidelines.

Basic Information

Product Name	Ethyl 3-(5-Chloro-2-Cyclopropoxyphenyl)-3-Oxopropanoate
CAS No.	1260169-30-9
Molecular Formula	C14H15ClO4
Molecular Weight	282.72 g/mol
Synonyms	Ethyl 3-(5-chloro-2-cyclopropoxyphenyl)-3-oxopropanoate; 3-Oxopropanoic acid, 3-(5-chloro-2-cyclopropoxyphenyl)-, ethyl ester; 5-Chloro-2-cyclopropoxyphenyl 3-oxo-propionate ethyl ester; Ethyl (5-chloro-2-cyclopropoxyphenyl) 3-oxopropanoate; Ethyl 3-oxo-3-(5-chloro-2-cyclopropoxyphenyl)propanoate; β-Keto ester derivative of 5-chloro-2-cyclopropoxyphenol
EINECS	Contact for details

Quality Control

Our production of Ethyl 3-(5-Chloro-2-Cyclopropoxyphenyl)-3-Oxopropanoate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material suitable for use under cGMP and ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.