Description

5-Isocyano-Pyridine-2,4-Diamine is a specialized heterocyclic building block featuring both isocyano and diamine functional groups on a pyridine scaffold. This unique bifunctional structure makes it a highly valuable intermediate for constructing complex molecular architectures in advanced chemical synthesis. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Ligand Synthesis: Serves as a versatile building block for creating sophisticated chelating ligands in coordination chemistry and catalysis.
• Material Science: Employed in the development of organic electronic materials and metal-organic frameworks (MOFs) due to its rigid, functionalizable structure.
• Chemical Biology Probes: Utilized to create isonitrile-based probes for bioorthogonal labeling and activity-based protein profiling.

Basic Information

Product Name	5-Isocyano-Pyridine-2,4-Diamine
CAS No.	1260157-25-2
Molecular Formula	C6H6N4
Molecular Weight	134.14 g/mol
Synonyms	2,4-Diamino-5-isocyanopyridine; 5-Isocyanopyridine-2,4-diamine; 2,4-Pyridinediamine, 5-isocyano-; 5-Isocyano-2,4-pyridinediamine
EINECS	Contact for details

Quality Control

Our 5-Isocyano-Pyridine-2,4-Diamine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.