Description

Benzyl-Peg2-Azide CAS NO 1260001-87-3 is a specialized bifunctional linker molecule featuring a benzyl group, a polyethylene glycol (PEG) spacer, and a terminal azide group. This compound is essential for facilitating click chemistry reactions, particularly copper-catalyzed azide-alkyne cycloaddition (CuAAC), enabling the efficient and selective conjugation of biomolecules, polymers, and surfaces. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotech, and materials science industries for applications in drug discovery, bioconjugation, and the development of functionalized nanomaterials.

Application

• Bioconjugation and Protein Labeling: Used as a linker to attach fluorescent dyes, drugs, or other functional moieties to antibodies, peptides, or proteins via click chemistry.
• Polymer and Dendrimer Functionalization: Serves as a key building block for introducing azide handles into polymer backbones or dendrimer surfaces for further modular assembly.
• Surface Modification and Immobilization: Enables the functionalization of solid supports, nanoparticles, or biosensor surfaces with azide groups for subsequent specific binding of alkyne-tagged molecules.
• Prodrug Synthesis: Facilitates the creation of cleavable linker systems in antibody-drug conjugates (ADCs) and other targeted therapeutic platforms.
• Chemical Biology Probes: Acts as a versatile tool for labeling and tracking cellular components in live-cell imaging and proteomics studies.
• Materials Science Research: Employed in the synthesis of novel hydrogels, smart materials, and self-assembled monolayers with tailored properties.

Basic Information

Product Name	Benzyl-Peg2-Azide
CAS No.	1260001-87-3
Molecular Formula	C14H19N3O3
Molecular Weight	277.32 g/mol
Synonyms	1-Azido-2-[2-(2-benzyloxy-ethoxy)-ethoxy]-ethane; 2-[2-(2-Benzyloxyethoxy)ethoxy]ethyl azide; Benzyl-PEG2-azide; Benzyl-triethylene glycol azide; Bn-PEG2-N3; Azido-PEG2-O-benzyl; 3,6,9-Trioxa-12-azadodec-11-en-1-yloxybenzene; Benzyl 2,2'-ethylenedioxyethyl ether azide
EINECS	Contact for details

Quality Control

Our Benzyl-Peg2-Azide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, NMR for structural confirmation, and mass spectrometry. We ensure compliance with relevant industry standards for research-grade chemicals. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.