Description

Methyl 6-Pivaloyl-4,5,6,7-Tetrahydrothieno[2,3-C]Pyridine-2-Carboxylate is a high-purity advanced pharmaceutical intermediate (API intermediate) with the CAS registry number 1259287-87-0. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular research. It is essential for pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical producers seeking reliable, high-quality intermediates for scalable synthesis.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel therapeutic agents, particularly for neurological and cardiovascular applications.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex drug molecules, leveraging its fused heterocyclic structure.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CMOs for process development, scale-up, and cGMP manufacturing of clinical trial materials.
• Reference Standard: Can be utilized as a chromatographic or spectroscopic standard for analytical method development and quality control.

Basic Information

Product Name	Methyl 6-Pivaloyl-4,5,6,7-Tetrahydrothieno[2,3-C]Pyridine-2-Carboxylate
CAS No.	1259287-87-0
Molecular Formula	C15H21NO3S
Molecular Weight	295.40 g/mol
Synonyms	Methyl 6-(2,2-dimethylpropanoyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-2-carboxylate; 6-Pivaloyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-2-carboxylic acid methyl ester; 2-Carbomethoxy-6-pivaloyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine; Thienopyridine derivative 1259287-87-0; Pivaloyl tetrahydrothienopyridine carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 6-Pivaloyl-4,5,6,7-Tetrahydrothieno[2,3-C]Pyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high standards, including pharmaceutical R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.