Description

3-Iodo-6,7-Dihydro-5H-Cyclopenta[B]Pyridine is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in enabling the construction of complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who require a reliable, high-purity intermediate for coupling reactions and structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with new modes of action.
• Material Science: Serves as a building block for creating organic electronic materials, such as ligands for OLEDs or charge-transport molecules.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Heck couplings due to the reactive iodine moiety.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Academic & Contract Research: A critical reagent for methodological development and discovery chemistry in academic and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	3-Iodo-6,7-Dihydro-5H-Cyclopenta[B]Pyridine
CAS No.	1259223-96-5
Molecular Formula	C8H8IN
Molecular Weight	245.06 g/mol
Synonyms	3-Iodocyclopentapyridine; 3-Iodo-6,7-dihydro-5H-cyclopenta[b]pyridine; 6,7-Dihydro-5H-cyclopenta[b]pyridin-3-yl iodide; 5H-Cyclopenta[b]pyridine, 3-iodo-6,7-dihydro-; Cyclopenta[b]pyridine, 3-iodo-6,7-dihydro-5H-
EINECS	Contact for details

Quality Control

Our 3-Iodo-6,7-Dihydro-5H-Cyclopenta[B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive research and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive compound from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.