Description

(R)-3-(4-Fluorophenyl)Piperidine CAS NO 1259007-80-1 is a high-purity chiral piperidine derivative, a critical building block in modern pharmaceutical research and development. Its value lies in its role as a versatile intermediate for synthesizing active pharmaceutical ingredients (APIs) and novel chemical entities, particularly those targeting the central nervous system. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in neurological and psychiatric therapeutic areas.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex molecules where the (R)-enantiomer configuration is required for biological activity.
• Medicinal Chemistry & Drug Discovery: Serves as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Research: Potential intermediate in the development of advanced pesticides and herbicides that utilize chiral chemistry for enhanced efficacy.
• Asymmetric Catalysis Ligand Precursor: Can be utilized to develop novel chiral ligands or organocatalysts for enantioselective synthesis.
• Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(R)-3-(4-Fluorophenyl)Piperidine
CAS No.	1259007-80-1
Molecular Formula	C11H14FN
Molecular Weight	179.24 g/mol
Synonyms	(R)-3-(4-Fluorophenyl)piperidine; (3R)-3-(4-Fluorophenyl)piperidine; (R)-3-(p-Fluorophenyl)piperidine; (R)-3-(4-Fluorophenyl)piperidine hydrochloride; (R)-3-(4-Fluorophenyl)piperidine HCl; (R)-3-(4-Fluorophenyl)piperidine HBr; (R)-3-(4-Fluorophenyl)piperidine hydrobromide; (R)-3-(4-Fluorophenyl)piperidine free base
EINECS	Contact for details

Quality Control

Our (R)-3-(4-Fluorophenyl)Piperidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.