Description

3-Hydroxy-4,5,6,7-Tetrahydro-2H-Pyrazolo[3,4-C]Pyridin-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrazolopyridine class of heterocyclic compounds. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of innovative therapeutic agents, particularly within central nervous system (CNS) and metabolic disorder research pipelines.

Application

This specialized intermediate serves as a key precursor in sophisticated organic synthesis. Its primary applications include:

• Pharmaceutical Intermediate: Core building block for the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new chemical entities.
• API Development: Integral in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs), especially those with fused heterocyclic structures.
• Biochemical Tool Compound: Potential use in the development of research-grade inhibitors or modulators for biological assays.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3-Hydroxy-4,5,6,7-Tetrahydro-2H-Pyrazolo[3,4-C]Pyridin-5-Carboxylic Acid
CAS No.	1258637-47-6
Molecular Formula	C7H9N3O3
Molecular Weight	183.16 g/mol
Synonyms	5-Carboxy-3-hydroxy-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridine; 3-Hydroxy-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridine-5-carboxylic acid; 2H-Pyrazolo[3,4-c]pyridine-5-carboxylic acid, 3-hydroxy-4,5,6,7-tetrahydro-; Pyrazolopyridine-5-carboxylic acid derivative; Fused pyrazolopyridine intermediate; CAS 1258637-47-6
EINECS	Contact for details

Quality Control

Our production of 3-Hydroxy-4,5,6,7-Tetrahydro-2H-Pyrazolo[3,4-C]Pyridin-5-Carboxylic Acid adheres to stringent quality management protocols. Every batch is subjected to rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and Mass Spectrometry, to ensure compliance with exacting customer specifications. Certificates of Analysis (COA) detailing all critical quality attributes are provided with each shipment. Our quality system supports development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.