Description

4-(2,4-Difluorophenyl)Picolinic Acid is a high-purity, functionalized picolinic acid derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which combines a difluorophenyl moiety with a picolinic acid core, enabling precise modifications in complex chemical pathways. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the difluorophenyl group can enhance biological activity and environmental stability.
• Ligand for Catalysis: Serves as a versatile ligand or precursor for metal-organic frameworks (MOFs) and transition metal catalysts in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its rigid, aromatic structure and potential for functionalization.
• Chemical Biology Probe: Utilized as a scaffold for designing molecular probes and inhibitors to study enzyme function and biological pathways.

Basic Information

Product Name	4-(2,4-Difluorophenyl)Picolinic Acid
CAS No.	1258626-21-9
Molecular Formula	C₁₂H₇F₂NO₂
Molecular Weight	235.19 g/mol
Synonyms	2-Pyridinecarboxylic acid, 4-(2,4-difluorophenyl)-; 4-(2,4-Difluorophenyl)pyridine-2-carboxylic acid; 4-(2,4-Difluorophenyl)-2-picolinic acid; 2,4-DFPA; 1258626-21-9; 4-(2,4-Difluorophenyl)picolinate
EINECS	Contact for details

Quality Control

Every batch of 4-(2,4-Difluorophenyl)Picolinic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications. Our quality protocols are designed to meet the rigorous standards required for pharmaceutical and fine chemical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.