Description

Spiro[4H-Azepine-4,2'(3'H)-Benzofuran], 5'-Bromo-1,2,3,5,6,7-Hexahydro- is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic molecular architecture. This compound is valued for its role as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold for constructing complex molecules in drug discovery programs, especially for probing new chemical space.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for the synthesis of novel spirocyclic and heterocyclic compounds.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Process Chemistry Development: Acts as a starting material for scaling up synthetic routes during pre-clinical and clinical manufacturing stages.

Basic Information

Product Name	Spiro[4H-Azepine-4,2'(3'H)-Benzofuran], 5'-Bromo-1,2,3,5,6,7-Hexahydro-
CAS No.	1258430-92-0
Molecular Formula	C14H16BrNO
Molecular Weight	294.19 g/mol
Synonyms	5'-Bromo-1,2,3,5,6,7-hexahydrospiro[benzofuran-2,4'-azepine]; 5'-Bromospiro[benzofuran-2,4'-azepine]; Spiro[benzofuran-2,4'-azepine], 5'-bromo-1,2,3,5,6,7-hexahydro-; 1258430-92-0; 5'-Bromo-hexahydro-spiro[benzofuran-2,4'-azepine]; Bromo-spiroazepine-benzofuran intermediate
EINECS	Contact for details

Quality Control

Our Spiro[4H-Azepine-4,2'(3'H)-Benzofuran], 5'-Bromo-1,2,3,5,6,7-Hexahydro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.