Description

Spiro[4H-Azepine-4,2'(3'H)-Benzofuran], 1,2,3,5,6,7-Hexahydro- is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic molecular architecture. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Used in scaling up and optimizing synthetic routes for potential new chemical entities (NCEs) under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical market.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Spiro[4H-Azepine-4,2'(3'H)-Benzofuran], 1,2,3,5,6,7-Hexahydro-
CAS No.	1258430-91-9
Molecular Formula	C14H17NO
Molecular Weight	215.29 g/mol
Synonyms	1,2,3,5,6,7-Hexahydrospiro[benzofuran-2,4'-azepine]; Spiro[benzofuran-2,4'-azepine], 1,2,3,5,6,7-hexahydro-; 1,2,3,5,6,7-Hexahydro-4H-spiro[benzofuran-2,4'-azepine]; Hexahydrospiro[benzofuran-2,4'-azepine]; CAS 1258430-91-9
EINECS	Contact for details

Quality Control

Our Spiro[4H-Azepine-4,2'(3'H)-Benzofuran], 1,2,3,5,6,7-Hexahydro- is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.