Description

(1S)- 6,6'-Bis([1,1'-Biphenyl]-4-Yl)-2,2',3,3'-Tetrahydro-1,1'-Spirobi[1H-Indene]-7,7'-Diol is a high-purity, chiral organic compound belonging to the class of spirobiindane derivatives. This compound is of significant commercial interest due to its utility as a key intermediate or ligand in advanced chemical synthesis, particularly in the development of pharmaceuticals and specialty materials. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors for applications requiring precise stereochemistry and functional group compatibility.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block or ligand in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) or cardiovascular drugs.
• Catalyst Ligand: Used in asymmetric catalysis, including hydrogenation or cross-coupling reactions, to induce high enantioselectivity in the production of fine chemicals.
• Agrochemical Research: Employed in the development of novel, enantiomerically pure pesticides and herbicides.
• Organic Light-Emitting Diodes (OLEDs): Investigated as a potential core structure for host or emissive materials in OLED devices due to its rigid, conjugated backbone.
• Liquid Crystal Materials: Acts as a precursor or dopant in the synthesis of advanced liquid crystals for display technologies.
• Polymer Science: Utilized as a monomer or cross-linking agent to create polymers with specific thermal and optical properties.
• Academic & R&D: A valuable compound for methodological studies in organic chemistry and material science research.

Basic Information

Product Name	(1S)- 6,6'-Bis([1,1'-Biphenyl]-4-Yl)-2,2',3,3'-Tetrahydro-1,1'-Spirobi[1H-Indene]-7,7'-Diol
CAS No.	1258327-00-2
Molecular Formula	C55H40O2
Molecular Weight	732.91 g/mol
Synonyms	(S)-6,6'-Bis([1,1'-biphenyl]-4-yl)-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol; (1S)-6,6'-Di([1,1'-biphenyl]-4-yl)-2,2',3,3'-tetrahydrospiro[1H-indene-7,7'-indene]-1,1'-diol; Spirobiindane Diol Derivative; (S)-Spirobiindanediol Derivative; CAS 1258327-00-2
EINECS	Contact for details

Quality Control

Our (1S)- 6,6'-Bis([1,1'-Biphenyl]-4-Yl)-2,2',3,3'-Tetrahydro-1,1'-Spirobi[1H-Indene]-7,7'-Diol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for research and industrial use. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.