Description

(1S)-2,2',3,3'-Tetrahydro-6,6'-Diiodo-1,1'-Spirobi[1H-Indene]-7,7'-Diol is a high-purity, chiral spirobiindane derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block and ligand precursor for the development of novel pharmaceuticals and specialty materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Asymmetric Catalysis: Used as a precursor for developing novel chiral ligands and catalysts for enantioselective synthesis, including cross-coupling and hydrogenation reactions.
• Material Science Research: Acts as a monomer or core structure for synthesizing advanced polymers, liquid crystals, or organic electronic materials with specific optical or electronic properties.
• Agrochemical Development: Employed in the research and development of new, more selective herbicides, fungicides, or plant growth regulators.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions due to its rigid, three-dimensional structure.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Detail
Product Name	(1S)-2,2',3,3'-Tetrahydro-6,6'-Diiodo-1,1'-Spirobi[1H-Indene]-7,7'-Diol
CAS No.	1258326-97-4
Molecular Formula	C17H14I2O2
Molecular Weight	528.10 g/mol
Synonyms	(1S)-6,6'-Diiodospirobiindane-7,7'-diol; (S)-6,6'-Diiodo-1,1'-spirobiindane-7,7'-diol; (1S)-6,6'-Diiodo-1,1'-spirobi[1H-indene]-7,7'-diol; (S)-Tetrahydrosiprobiindane diiodo diol; (S)-Spirobiindane diiodo diol derivative; (1S)-THSBI-I2-diol; Chiral spiro diiodo diol; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (1S)-2,2',3,3'-Tetrahydro-6,6'-Diiodo-1,1'-Spirobi[1H-Indene]-7,7'-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric excess, to meet exacting R&D and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.