Description

4-(6-Methyl-4,8-dioxo-1,3,6,2-dioxazaborocan-2-yl)benzaldehyde is a specialized boron-containing heterocyclic aldehyde building block. This compound matters for its role as a key intermediate in the synthesis of complex molecules, particularly in advanced materials and pharmaceutical research. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced organic electronics industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of boron-containing active pharmaceutical ingredients (APIs), especially for proteolysis-targeting chimeras (PROTACs) and other novel therapeutic modalities.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides where the boron heterocycle imparts unique biological activity.
• Material Science: Serves as a building block for boron-doped organic semiconductors, liquid crystals, and polymers with tailored electronic or optical properties.
• Cross-Coupling Reactions: The aldehyde functional group allows for further derivatization via reactions like reductive amination or condensation, while the boron moiety can participate in Suzuki-Miyaura cross-couplings.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme activity and protein-protein interactions.
• Ligand Synthesis: Used to create novel chelating ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Product Name	4-(6-Methyl-4,8-dioxo-1,3,6,2-dioxazaborocan-2-yl)benzaldehyde
CAS No.	1257650-77-3
Molecular Formula	C13H12BNO5
Molecular Weight	273.05 g/mol
Synonyms	4-(6-Methyl-4,8-dioxo-1,3,6,2-dioxazaborocan-2-yl)benzaldehyde; 2-(4-Formylphenyl)-6-methyl-1,3,6,2-dioxazaborocane-4,8-dione; Benzaldehyde, 4-(6-methyl-4,8-dioxo-1,3,6,2-dioxazaborocan-2-yl)-; Boronic acid, B-[4-(formyl)phenyl]-, 2,2'-(1-methylethylidene)bis[4,4,5,5-tetramethyl-1,3,2-dioxaborolane] derivative (related precursor); 4-(Dioxaborolanyl)benzaldehyde derivative
EINECS	Contact for details

Quality Control

Our 4-(6-Methyl-4,8-dioxo-1,3,6,2-dioxazaborocan-2-yl)benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.