Description

(R)-1-(5-Bromo-Pyridin-2-Yl)-Ethylamine Dihydrochloride is a high-purity chiral amine derivative, specifically the (R)-enantiomer, which serves as a critical building block in modern organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules with defined stereochemistry, essential for developing active pharmaceutical ingredients (APIs) and advanced materials. This compound is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and antiviral therapies.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Ligand Precursor: Serves as a starting material for the synthesis of chiral ligands used in catalysis, such as for asymmetric hydrogenation or cross-coupling reactions.
• Agrochemical Research: Employed in the development of novel, enantiomerically pure pesticides and herbicides where specific stereochemistry impacts biological activity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Material Science: A potential monomer or precursor for creating chiral polymers and advanced functional materials with specific optical properties.

Basic Information

Product Name	(R)-1-(5-Bromo-Pyridin-2-Yl)-Ethylamine Dihydrochloride
CAS No.	1257638-63-3
Molecular Formula	C7H10BrCl2N2
Molecular Weight	282.98 g/mol
Synonyms	(R)-1-(5-Bromopyridin-2-yl)ethan-1-amine dihydrochloride; (R)-1-(5-Bromo-2-pyridinyl)ethylamine dihydrochloride; (R)-α-Methyl-5-bromo-2-pyridinemethanamine dihydrochloride; (R)-5-Bromo-2-(1-aminoethyl)pyridine dihydrochloride; (R)-1-(5-Bromo-2-pyridyl)ethylamine hydrochloride (1:2); (R)-5-Bromo-2-(α-aminoethyl)pyridine dihydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(5-Bromo-Pyridin-2-Yl)-Ethylamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.