Description

(6-Chloro-5-Methoxypyridin-3-Yl)Methanamine Hydrochloride is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key chiral intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly in complex therapeutic areas. Pharmaceutical R&D and fine chemical manufacturers need this material for constructing sophisticated molecular architectures where precise substitution on the pyridine ring is essential for biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in oncology, neurology, and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the chloromethoxypyridine scaffold imparts specific biological properties.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional organic molecules for electronic materials and advanced polymers.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for studying biological pathways and target engagement.

Basic Information

Item	Detail
Product Name	(6-Chloro-5-Methoxypyridin-3-Yl)Methanamine Hydrochloride
CAS No.	1257535-63-9
Molecular Formula	C7H10Cl2N2O
Molecular Weight	209.07 g/mol
Synonyms	1-(6-Chloro-5-methoxypyridin-3-yl)methanamine hydrochloride; (6-Chloro-5-methoxy-3-pyridinyl)methanamine hydrochloride; 3-(Aminomethyl)-6-chloro-5-methoxypyridine hydrochloride; 5-(Aminomethyl)-2-chloro-3-methoxypyridine hydrochloride; 6-Chloro-5-methoxy-3-pyridinemethanamine HCl; CAS 1257535-63-9
EINECS	Contact for details

Quality Control

Our (6-Chloro-5-Methoxypyridin-3-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our commitment to quality supports compliance in cGMP and ISO 9001 environments for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.