Description

(3-Bromo-5-Chloropyridin-2-Yl)Methanamine Hydrochloride is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate, enabling the precise introduction of both bromo and chloro substituents alongside an amine handle for further derivatization. It is primarily needed by pharmaceutical and agrochemical R&D teams for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in constructing advanced pesticide and herbicide molecules, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functional organic materials and electronic chemicals.
• Custom Synthesis and Contract Manufacturing: A requested intermediate for bespoke chemical synthesis services in fine chemical production.
• Academic and R&D Laboratories: Used in exploratory chemistry for method development and novel heterocyclic compound libraries.

Basic Information

Product Name	(3-Bromo-5-Chloropyridin-2-Yl)Methanamine Hydrochloride
CAS No.	1257535-43-5
Molecular Formula	C6H7BrCl2N2
Molecular Weight	266.95 g/mol
Synonyms	1-(3-Bromo-5-chloropyridin-2-yl)methanamine hydrochloride; 2-(Aminomethyl)-3-bromo-5-chloropyridine hydrochloride; (3-Bromo-5-chloro-2-pyridinyl)methanamine hydrochloride; 3-Bromo-5-chloro-2-pyridinemethanamine hydrochloride; 2-Aminomethyl-3-bromo-5-chloropyridine HCl; (3-Bromo-5-chloro-pyridin-2-yl)-methylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (3-Bromo-5-Chloropyridin-2-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.