Description

(5-Bromo-3-Fluoropyridin-2-Yl)Methanamine Hydrochloride is a high-value, halogenated pyridine derivative building block essential for modern pharmaceutical and agrochemical research. Its core value lies in providing a versatile scaffold for constructing complex molecules, enabling the development of novel active ingredients. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for use in drug discovery, crop protection, and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated pyridine core.
• Chemical Biology & Proteomics: Serves as a versatile linker or functional handle in the design of chemical probes and affinity tags for target identification and validation.
• Material Science: Employed as a precursor for creating functionalized polymers, ligands for catalysis, and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	(5-Bromo-3-Fluoropyridin-2-Yl)Methanamine Hydrochloride
CAS No.	1257535-19-5
Molecular Formula	C6H7BrClFN2
Molecular Weight	225.49 g/mol
Synonyms	2-(Aminomethyl)-5-bromo-3-fluoropyridine hydrochloride; 1-(5-Bromo-3-fluoropyridin-2-yl)methanamine hydrochloride; (5-Bromo-3-fluoro-2-pyridinyl)methanamine hydrochloride; 5-Bromo-3-fluoro-2-pyridinemethanamine HCl; 2-Pyridinemethanamine, 5-bromo-3-fluoro-, hydrochloride; 5-Bromo-3-fluoropyridin-2-ylmethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (5-Bromo-3-Fluoropyridin-2-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.