Description

5-Boc-Octahydro-Pyrrolo[3,4-C]Pyridine is a protected bicyclic amine derivative, serving as a crucial advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its core value lies in its rigid, nitrogen-containing fused ring system, which is highly sought after for constructing complex molecular architectures with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients in drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Organic Synthesis Scaffold: Used as a versatile precursor for constructing complex, polycyclic nitrogen-containing heterocycles due to its fused pyrrolidine-pyridine structure.
• Medicinal Chemistry Research: Employed in high-throughput screening and structure-activity relationship (SAR) studies to explore new bioactive molecules.
• Agrochemical Development: Intermediate in the synthesis of novel herbicides, fungicides, and insecticides that require specific chiral amine components.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized bicyclic amines.

Basic Information

Product Name	5-Boc-Octahydro-Pyrrolo[3,4-C]Pyridine
CAS No.	1257389-94-8
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	1-Boc-Octahydro-Pyrrolo[3,4-c]pyridine; tert-Butyl Octahydro-1H-pyrrolo[3,4-c]pyridine-1-carboxylate; 1H-Pyrrolo[3,4-c]pyridine-1-carboxylic acid, 2,3,3a,4,6,7,7a,8-octahydro-, 1,1-dimethylethyl ester; 5-(tert-Butoxycarbonyl)octahydropyrrolo[3,4-c]pyridine; Octahydro-1H-pyrrolo[3,4-c]pyridine-1-carboxylic acid tert-butyl ester; Bicyclic Boc-protected amine; 5-Boc-Octahydro-Pyrrolo[3,4-C]Pyridine.
EINECS	Contact for details

Quality Control

Our 5-Boc-Octahydro-Pyrrolo[3,4-C]Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.