Description

4-Bromo-3-Iodo-Benzoic Acid Methyl Ester is a high-purity halogenated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex molecules, particularly in pharmaceutical and agrochemical research. It is needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for constructing novel chemical entities and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those requiring halogenated aromatic motifs.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides where the bromo and iodo substituents can be leveraged for further functionalization.
• Material Science Precursor: Serves as a monomer or starting material for synthesizing specialized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) due to the presence of both bromine and iodine, which have different reactivity profiles.
• Ligand and Catalyst Synthesis: Employed in the preparation of complex ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Useful for creating tagged molecules or probes for studying biological systems and mechanisms.

Basic Information

Product Name	4-Bromo-3-Iodo-Benzoic Acid Methyl Ester
CAS No.	1257231-51-8
Molecular Formula	C8H6BrIO2
Molecular Weight	340.94 g/mol
Synonyms	Methyl 4-Bromo-3-Iodobenzoate; Benzoic acid, 4-bromo-3-iodo-, methyl ester; 4-Bromo-3-iodobenzoic acid methyl ester; Methyl 4-bromo-3-iodobenzoate; 1257231-51-8; 4-Br-3-I-C6H2-COOCH3; 3-Iodo-4-bromobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Iodo-Benzoic Acid Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of our global pharmaceutical and fine chemical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.