Description

1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid Ethyl Ester is a high-value heterocyclic building block of significant importance in modern pharmaceutical and agrochemical research. Its fused pyrazolopyridine core serves as a privileged scaffold for designing novel bioactive molecules, offering a versatile handle for further synthetic elaboration. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of advanced intermediates and active ingredients.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology: Employed as a molecular probe or scaffold in the design of chemical tools for studying biological processes.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploration of new chemical space.
• Custom Synthesis: A starting material for the contract manufacturing of complex, proprietary molecules for client-specific applications.

Basic Information

Product Name	1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid Ethyl Ester
CAS No.	1256824-48-2
Molecular Formula	C10H9N3O2
Molecular Weight	203.20 g/mol
Synonyms	Ethyl 1H-pyrazolo[3,4-b]pyridine-5-carboxylate; 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic acid, ethyl ester; Ethyl 1H-pyrazolo[3,4-b]pyridine-5-carboxylate; 5-(Ethoxycarbonyl)-1H-pyrazolo[3,4-b]pyridine; Pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester; 1256824-48-2; 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥97.0% (Standard Grade) ≥98.0% (High Purity Grade)
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.