Description

6-(Difluoromethyl)-2-Pyridinecarboxylic Acid is a high-value pyridine derivative and a versatile fluorinated building block in advanced organic synthesis. Its molecular structure, featuring both a carboxylic acid group and a difluoromethyl substituent, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides, where the difluoromethyl group can enhance bioavailability and stability.
• Ligand and Catalyst Development: Used in the design of novel ligands for metal-organic frameworks (MOFs) and catalysts for asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic electronic materials that require fluorinated components.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	6-(Difluoromethyl)-2-Pyridinecarboxylic Acid
CAS No.	1256824-41-5
Molecular Formula	C7H5F2NO2
Molecular Weight	173.12 g/mol
Synonyms	2-Pyridinecarboxylic acid, 6-(difluoromethyl)-; 6-(Difluoromethyl)picolinic acid; 6-Difluoromethylpyridine-2-carboxylic acid; 2-Carboxy-6-(difluoromethyl)pyridine; 6-Difluoromethyl-2-pyridinecarboxylic acid; Difluoromethylpicolinic acid
EINECS	Contact for details

Quality Control

Our 6-(Difluoromethyl)-2-Pyridinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.