Description

(5-Fluoro-2-Methoxypyridin-4-Yl)Methanamine is a high-value pyridine derivative building block, specifically a fluorinated methoxypyridinemethanamine, essential for advanced organic synthesis. Its core value lies in its unique molecular scaffold, which combines a fluorine atom and a methoxy group on a pyridine ring with a primary amine side chain, enabling precise structural modifications in target molecules. This compound is critically needed by pharmaceutical, agrochemical, and advanced materials research sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for constructing complex ligands in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe Synthesis: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Material Science Research: Utilized as a monomer or functionalizing agent in the development of specialty polymers and advanced organic electronic materials.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	(5-Fluoro-2-Methoxypyridin-4-Yl)Methanamine
CAS No.	1256824-28-8
Molecular Formula	C7H9FN2O
Molecular Weight	156.16 g/mol
Synonyms	4-(Aminomethyl)-5-fluoro-2-methoxypyridine; 1-(5-Fluoro-2-methoxypyridin-4-yl)methanamine; (5-Fluoro-2-methoxy-4-pyridinyl)methanamine; 4-Pyridinemethanamine, 5-fluoro-2-methoxy-; 5-Fluoro-2-methoxy-4-pyridinemethanamine; 5-Fluoro-2-methoxyisonicotinylamine; 5-Fluoro-2-methoxy-4-pyridylmethylamine
EINECS	Contact for details

Quality Control

Our (5-Fluoro-2-Methoxypyridin-4-Yl)Methanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.