Description

2-Bromo-5-Chloropyridine-3-Carbonitrile is a high-value halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an essential intermediate for constructing complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is primarily sought after by research chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a functional monomer or cross-linking agent in the development of specialty polymers and liquid crystals.
• Chemical Biology: Employed as a versatile scaffold for creating molecular probes and labeled compounds for biological studies.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Bromo-5-Chloropyridine-3-Carbonitrile
CAS No.	1256823-81-0
Molecular Formula	C6H2BrClN2
Molecular Weight	217.45 g/mol
Synonyms	3-Cyano-2-bromo-5-chloropyridine; 5-Chloro-2-bromonicotinonitrile; 2-Bromo-5-chloro-3-pyridinecarbonitrile; 2-Bromo-5-chloro-3-cyanopyridine; 5-Chloro-2-bromo-3-cyanopyridine; Nicotinonitrile, 2-bromo-5-chloro-; 2-Bromo-5-chloropyridine-3-carbonitrile (IUPAC); 1256823-81-0
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Chloropyridine-3-Carbonitrile is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support cGMP and ISO 9001 compliant production for pharmaceutical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.