Description

5-Bromo-6-Fluoro-Nicotinonitrile CAS NO 1256823-71-8 is a high-value halogenated pyridine derivative, a crucial building block in modern organic synthesis. Its molecular structure, featuring both bromine and fluorine substituents on the pyridine core, makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated heterocycles.
• Material Science: Serves as a building block for advanced organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactivity of the bromine substituent, enabling rapid diversification of chemical libraries.
• Life Science Research: Utilized as a biochemical probe or a labeled compound in medicinal chemistry and drug discovery programs.

Basic Information

Product Name	5-Bromo-6-Fluoro-Nicotinonitrile
CAS No.	1256823-71-8
Molecular Formula	C6H2BrFN2
Molecular Weight	200.99 g/mol
Synonyms	5-Bromo-6-fluoronicotinonitrile; 3-Cyano-5-bromo-6-fluoropyridine; 5-Bromo-6-fluoro-3-pyridinecarbonitrile; 6-Fluoro-5-bromonicotinonitrile; Nicotinonitrile, 5-bromo-6-fluoro-; Pyridine, 3-cyano-5-bromo-6-fluoro-
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-6-Fluoro-Nicotinonitrile is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.