Description

1-(3-Bromo-5-Chloropyridin-2-Yl)Ethanone CAS NO 1256823-11-6 is a high-purity, halogenated pyridine derivative serving as a critical advanced pharmaceutical intermediate and organic synthesis building block. Its unique structure, featuring both bromo and chloro substituents on the pyridine ring, makes it an essential precursor for constructing complex molecules in medicinal chemistry. This compound is primarily required by pharmaceutical R&D and fine chemical synthesis sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its bioactive pyridine core.
• Material Science Research: Serves as a monomer or precursor for creating functional polymers and liquid crystals.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce functionalized pyridine motifs.
• Chemical Reference Standard: Used for analytical method development and quality control in chemical manufacturing.

Basic Information

Product Name	1-(3-Bromo-5-Chloropyridin-2-Yl)Ethanone
CAS No.	1256823-11-6
Molecular Formula	C7H5BrClNO
Molecular Weight	234.48 g/mol
Synonyms	2-Acetyl-3-bromo-5-chloropyridine; 3-Bromo-5-chloro-2-acetylpyridine; 1-(3-Bromo-5-chloro-2-pyridinyl)ethanone; Ethanone, 1-(3-bromo-5-chloro-2-pyridinyl)-; 3-Bromo-5-chloropyridin-2-yl methyl ketone
EINECS	Contact for details

Quality Control

Our 1-(3-Bromo-5-Chloropyridin-2-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, impurity profiles, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.