Description

5-Bromo-4-Methoxypicolinonitrile CAS NO 1256823-07-0 is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. Its unique molecular structure, featuring a bromine substituent and a nitrile group on a methoxypyridine scaffold, makes it a critical intermediate for constructing complex pharmacophores. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science: Serves as a building block for creating functionalized ligands in catalysis and for synthesizing advanced organic electronic materials.
• Chemical Biology: Employed as a probe or labeling agent in bioconjugation chemistry due to its reactive bromine and nitrile functional groups.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs engaged in bespoke chemical synthesis projects.

Basic Information

Product Name	5-Bromo-4-Methoxypicolinonitrile
CAS No.	1256823-07-0
Molecular Formula	C7H5BrN2O
Molecular Weight	213.04 g/mol
Synonyms	5-Bromo-4-methoxypyridine-2-carbonitrile; 4-Methoxy-5-bromopicolinonitrile; 2-Cyano-5-bromo-4-methoxypyridine; 5-Bromo-4-methoxy-2-pyridinecarbonitrile; 1256823-07-0; 5-Br-4-MeO-picolinonitrile
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-4-Methoxypicolinonitrile is manufactured under strict quality management protocols. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request, providing full traceability and assurance for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.