Description

2-Pyridinecarboxylic Acid, 5-Fluoro-4-Methoxy-, Methyl Ester is a high-purity fluorinated pyridine derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates fluorine and methoxy substituents to modulate reactivity and physicochemical properties for targeted applications. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced organic electronic materials and liquid crystals due to its electron-deficient pyridine core.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes to study biological systems.
• Custom Synthesis and Scale-Up: Available for contract research organizations (CROs) and CDMOs requiring a reliable, high-quality intermediate for custom synthesis projects from gram to kilogram scale.

Basic Information

Product Name	2-Pyridinecarboxylic Acid, 5-Fluoro-4-Methoxy-, Methyl Ester
CAS No.	1256822-42-0
Molecular Formula	C8H8FNO3
Molecular Weight	185.15 g/mol
Synonyms	Methyl 5-Fluoro-4-methoxypicolinate; 5-Fluoro-4-methoxypicolinic Acid Methyl Ester; 5-Fluoro-4-methoxy-2-pyridinecarboxylic Acid Methyl Ester; Methyl 5-Fluoro-4-methoxy-2-pyridinecarboxylate; 2-Pyridinecarboxylic Acid, 5-Fluoro-4-Methoxy-, Methyl Ester; 5-Fluoro-4-methoxypicolinate Methyl Ester; 1256822-42-0
EINECS	Contact for details

Quality Control

Every batch of 2-Pyridinecarboxylic Acid, 5-Fluoro-4-Methoxy-, Methyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.