Description

Methyl 3-Fluoro-6-Methylpyridine-2-Carboxylate is a high-purity fluorinated pyridine derivative, a critical building block in modern organic synthesis. This compound matters for its role as a versatile intermediate in the development of advanced pharmaceuticals and agrochemicals, where the fluorine atom and ester functionality enable precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the fluorine substituent.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the creation of functionalized heterocyclic compounds for advanced polymers and electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated pyridine scaffolds.
• Academic and Industrial R&D: Utilized in research laboratories for methodological studies and exploring new chemical spaces in medicinal and synthetic chemistry.

Basic Information

Product Name	Methyl 3-Fluoro-6-Methylpyridine-2-Carboxylate
CAS No.	1256822-15-7
Molecular Formula	C8H8FNO2
Molecular Weight	169.15 g/mol
Synonyms	2-Pyridinecarboxylic acid, 3-fluoro-6-methyl-, methyl ester; Methyl 3-fluoro-6-picolinate; 3-Fluoro-6-methylpyridine-2-carboxylic acid methyl ester; 3-Fluoro-6-methyl-2-pyridinecarboxylic acid methyl ester; 2-Methoxycarbonyl-3-fluoro-6-methylpyridine; 3-Fluoro-6-methylpicolinic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Fluoro-6-Methylpyridine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee batch-to-batch consistency and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.