Description

Ethyl 6-Chloro-5-Hydroxynicotinate is a high-purity organic intermediate of significant importance in advanced chemical synthesis. This compound matters for its role as a versatile building block in the development of complex molecules, particularly within the pharmaceutical and agrochemical sectors. It is primarily needed by research institutions and industrial manufacturers engaged in the production of active pharmaceutical ingredients (APIs), fine chemicals, and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Serves as a crucial precursor in the manufacturing of advanced herbicides and insecticides, contributing to new modes of action.
• Fine Chemical Production: Used in custom synthesis and contract manufacturing for specialty chemicals requiring a functionalized nicotinate core.
• Academic & Industrial R&D: Employed in chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Material Science Research: Potential building block for organic electronic materials and ligands in catalytic systems.

Basic Information

Product Name	Ethyl 6-Chloro-5-Hydroxynicotinate
CAS No.	1256807-18-7
Molecular Formula	C8H8ClNO3
Molecular Weight	201.61 g/mol
Synonyms	Ethyl 6-chloro-5-hydroxypyridine-3-carboxylate; 5-Hydroxy-6-chloronicotinic acid ethyl ester; 6-Chloro-5-hydroxy-3-pyridinecarboxylic acid ethyl ester; 3-Pyridinecarboxylic acid, 6-chloro-5-hydroxy-, ethyl ester; Ethyl 6-chloro-5-oxo-1,6-dihydropyridine-3-carboxylate (tautomer)
EINECS	Contact for details

Quality Control

Our Ethyl 6-Chloro-5-Hydroxynicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.