Description

Spiro[Benzofuran-3(2H),4'-Piperidine], 5-Bromo- is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic molecular architecture. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and oncology drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel small-molecule drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic targets.
• CNS Drug Discovery: Serves as a core scaffold for compounds targeting neurological and psychiatric disorders.
• Oncology Research: Employed in the synthesis of potential kinase inhibitors and other anti-cancer agents.
• Chemical Biology: Used as a probe or ligand in the study of biological pathways and protein interactions.
• Process Chemistry Development: Scaled for use in route scouting and optimization for commercial API manufacturing.

Basic Information

Product Name	Spiro[Benzofuran-3(2H),4'-Piperidine], 5-Bromo-
CAS No.	1256794-00-9
Molecular Formula	C13H14BrNO
Molecular Weight	280.16 g/mol
Synonyms	5-Bromospiro[benzofuran-3(2H),4'-piperidine]; 5-Bromo-2,3-dihydrospiro[benzofuran-3,4'-piperidine]; 5-Bromo-2H-spiro[benzofuran-3,4'-piperidine]; 5-Bromo-2,3-dihydro-1-benzofuran-3-spiro-4'-piperidine; 5-Bromo-spiro(2,3-dihydrobenzofuran-3,4'-piperidine); 1256794-00-9; Spiro[benzofuran-3(2H),4'-piperidine], 5-bromo-
EINECS	Contact for details

Quality Control

Our Spiro[Benzofuran-3(2H),4'-Piperidine], 5-Bromo- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles suitable for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.