Description

4-Pyridinecarboxylic Acid, 3-Chloro-5-Methyl-, Methyl Ester is a high-purity, synthetically valuable pyridine derivative. This compound serves as a crucial advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for drug discovery programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Building block for developing new-generation herbicides, fungicides, and insecticides with improved efficacy.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Intermediate for synthesizing functionalized pyridine-based polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	4-Pyridinecarboxylic Acid, 3-Chloro-5-Methyl-, Methyl Ester
CAS No.	1256791-82-8
Molecular Formula	C8H8ClNO2
Molecular Weight	185.61 g/mol
Synonyms	Methyl 3-Chloro-5-methylisonicotinate; 3-Chloro-5-methylisonicotinic acid methyl ester; 3-Chloro-5-methylpyridine-4-carboxylic acid methyl ester; 4-Pyridinecarboxylic acid, 3-chloro-5-methyl-, methyl ester; Isonicotinic acid, 3-chloro-5-methyl-, methyl ester
EINECS	Contact for details

Quality Control

Our 4-Pyridinecarboxylic Acid, 3-Chloro-5-Methyl-, Methyl Ester is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure high chemical purity and lot-to-lot consistency, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.