Description

2-Methyl-6-(Trifluoromethyl)Pyridin-3-Ol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethyl group and a hydroxyl substituent, makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in areas like kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves efficacy and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.

Basic Information

Item	Details
Product Name	2-Methyl-6-(Trifluoromethyl)Pyridin-3-Ol
CAS No.	1256791-52-2
Molecular Formula	C7H6F3NO
Molecular Weight	177.12 g/mol
Synonyms	3-Hydroxy-2-methyl-6-(trifluoromethyl)pyridine; 6-(Trifluoromethyl)-2-methylpyridin-3-ol; 2-Methyl-6-trifluoromethyl-3-pyridinol; 2-Methyl-6-(trifluoromethyl)-3-hydroxypyridine; 3-Pyridinol, 2-methyl-6-(trifluoromethyl)-; 2-Methyl-6-(trifluoromethyl)-3-pyridol
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-6-(Trifluoromethyl)Pyridin-3-Ol is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques like HPLC, GC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.