Description

6-Bromo-2-Methoxynicotinonitrile is a versatile and high-value brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromine and nitrile functional groups, makes it an essential intermediate for constructing complex molecules with precision. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated pyridine core.
• Material Science Research: Serves as a precursor for ligands in catalytic systems or for creating functionalized polymers and dyes.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitution reactions due to the reactive bromine atom.
• Academic & Contract Research: Utilized in university and CRO laboratories for method development and exploring new chemical spaces.

Basic Information

Product Name	6-Bromo-2-Methoxynicotinonitrile
CAS No.	1256790-45-0
Molecular Formula	C7H5BrN2O
Molecular Weight	213.03 g/mol
Synonyms	2-Methoxy-6-bromonicotinonitrile; 6-Bromo-2-methoxypyridine-3-carbonitrile; 3-Cyano-6-bromo-2-methoxypyridine; 2-Bromo-5-cyano-6-methoxypyridine; Nicotinonitrile, 6-bromo-2-methoxy-; 1256790-45-0; 6-Bromo-2-methoxy-3-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-2-Methoxynicotinonitrile is produced and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under a dry inert atmosphere for long-term storage to maintain stability and purity. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.