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5-Bromo-4-Chloro-2-Cyanopyridine CAS NO 1256790-41-6
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CAS No.:1256790-41-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
5-Bromo-4-Chloro-2-Cyanopyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its versatile reactivity, enabling the construction of complex molecular architectures for research and development. This compound is essential for pharmaceutical chemists and agrochemical researchers developing novel active ingredients, particularly in medicinal chemistry for creating targeted small-molecule libraries.
Application
- Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
- Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogen and nitrile functionality.
- Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystal materials.
- Chemical Synthesis: Acts as a versatile scaffold for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to introduce complex substituents.
- Bioconjugation & Probe Development: Utilized in designing molecular probes and tags for biochemical and diagnostic applications.
Basic Information
| Product Name | 5-Bromo-4-Chloro-2-Cyanopyridine |
| CAS No. | 1256790-41-6 |
| Molecular Formula | C6H2BrClN2 |
| Molecular Weight | 217.45 g/mol |
| Synonyms | 4-Chloro-5-bromo-2-cyanopyridine; 2-Cyano-5-bromo-4-chloropyridine; 5-Bromo-4-chloro-2-pyridinecarbonitrile; 2-Pyridinecarbonitrile, 5-bromo-4-chloro-; 1256790-41-6; Br,4-Cl-2-CN-Pyridine |
| EINECS | Contact for details |
Quality Control
Our 5-Bromo-4-Chloro-2-Cyanopyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available for every shipment to support your quality assurance and regulatory needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (HPLC) | Conforms to reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Related Substances (HPLC) | Total impurities ≤ 2.0% |
| Residual Solvents (GC) | Meets ICH Q3C guidelines |
| Water Content (KF) | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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