Description

5-Bromo-4-Methoxy-2-(Trifluoromethyl)Pyridine is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, methoxy, and trifluoromethyl substituents, provides versatile reactivity for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, including herbicides and fungicides, leveraging the biological activity imparted by the trifluoromethylpyridine moiety.
• Material Science Precursor: Serves as a specialized monomer or ligand in the synthesis of functional polymers, liquid crystals, and electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Negishi) to form new carbon-carbon bonds.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Item	Details
Product Name	5-Bromo-4-Methoxy-2-(Trifluoromethyl)Pyridine
CAS No.	1256790-33-6
Molecular Formula	C8H5BrF3NO
Molecular Weight	256.03 g/mol
Synonyms	5-Bromo-4-methoxy-2-(trifluoromethyl)pyridine; 2-(Trifluoromethyl)-5-bromo-4-methoxypyridine; 4-Methoxy-5-bromo-2-trifluoromethylpyridine; 5-Bromo-4-methoxy-2-trifluoromethylpyridine; 1256790-33-6
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-4-Methoxy-2-(Trifluoromethyl)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, NMR, and other relevant techniques is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/GC)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.