Description

5-Chloro-6-Fluoropyridin-3-Amine CAS NO 1256790-26-7 is a high-purity, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which provides a versatile scaffold for constructing complex molecules with targeted biological or material properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Material Science Precursor: Serves as a starting material for synthesizing specialized ligands, catalysts, and functionalized polymers.
• Chemical Research: Employed in academic and industrial R&D for exploring new heterocyclic chemistry, cross-coupling reactions, and structure-activity relationship (SAR) studies.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex colorants and functional dyes.

Basic Information

Product Name	5-Chloro-6-Fluoropyridin-3-Amine
CAS No.	1256790-26-7
Molecular Formula	C5H4ClFN2
Molecular Weight	146.55 g/mol
Synonyms	3-Amino-5-chloro-6-fluoropyridine; 5-Chloro-6-fluoro-3-pyridinamine; 5-Chloro-6-fluoropyridin-3-ylamine; 6-Fluoro-5-chloropyridin-3-amine; 3-Pyridinamine, 5-chloro-6-fluoro-; 1256790-26-7
EINECS	Contact for details

Quality Control

Our production of 5-Chloro-6-Fluoropyridin-3-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.