Description

6-Chloro-2-Iodo-3-Methoxy-Pyridine is a high-purity halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which provides distinct reactivity for constructing complex heterocyclic scaffolds. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialized polymers and liquid crystals.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Chemical Synthesis: Employed as a versatile scaffold for further functionalization to create libraries of novel heterocyclic compounds for screening.

Basic Information

Product Name	6-Chloro-2-Iodo-3-Methoxy-Pyridine
CAS No.	1256790-05-2
Molecular Formula	C6H5ClINO
Molecular Weight	269.47 g/mol
Synonyms	2-Iodo-6-chloro-3-methoxypyridine; 3-Methoxy-6-chloro-2-iodopyridine; 6-Chloro-2-iodo-3-methoxypyridine; 2-Iodo-3-methoxy-6-chloropyridine; 6-Chloro-3-methoxy-2-iodopyridine
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Iodo-3-Methoxy-Pyridine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) are available for every batch upon request, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.