Description

3-Bromo-2-Fluoro-4-Methoxy-Pyridine CAS NO 1256789-70-4 is a high-purity, multi-functional halogenated pyridine derivative designed for advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and agrochemical building block, enabling the introduction of both bromine and fluorine substituents in a single, reactive scaffold. It is essential for research and production in life sciences, material science, and fine chemical manufacturing, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for functionalized ligands, organic semiconductors, and liquid crystal materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the reactive bromine atom.
• Fluorine Chemistry: Provides a stable platform for further fluorination or functionalization studies in medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for proprietary synthesis projects and scale-up development.

Basic Information

Product Name	3-Bromo-2-Fluoro-4-Methoxy-Pyridine
CAS No.	1256789-70-4
Molecular Formula	C6H5BrFNO
Molecular Weight	206.01 g/mol
Synonyms	2-Fluoro-3-bromo-4-methoxypyridine; 4-Methoxy-3-bromo-2-fluoropyridine; 3-Bromo-2-fluoro-4-methoxypyridine; Pyridine, 3-bromo-2-fluoro-4-methoxy-; 1256789-70-4
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Fluoro-4-Methoxy-Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.